The Mekong Delta is certainly one of the highlights in southern Vietnam. A trip to this area is often in the itinerary during a visit to Vietnam. Unfortunately, it seems many visitors only stay for a couple of days, covering the main tourists’ centres like Can Tho, My Tho or Ben Tre. While these places are very interesting (and I love Can Tho), the Mekong Delta has much more to offer. And for me the best way to explore it is by doing a Mekong Delta motorbike trip. This way you can experience not just the sight, but also interact with locals and see more of the real rural Vietnam.
One very interesting tour is the Mekong Delta Border Loop, a tour from HCMC to the border of Cambodia and back to HCMC.